| Shadow Bolt, Rank 13 (Shadow) | 331,113 | 15.2% | 28/28 | 6,397 | 11,825 | 20,815 | 42.9% | | 3.9% | | | | | | |
| Corruption, Rank 10 (Shadow) | 284,177 | 13.1% | | | | | | | | | 50 | 2,572 | 5,684 | 10,944 | 3.9% |
| Starfire, Rank 10 (Arcane) | 252,113 | 11.6% | 14/14 | 8,235 | 18,008 | 21,708 | 85.7% | | 3.1% | | | | | | |
| Mind Flay, Rank 9 (Shadow) | 168,729 | 7.8% | 37/37 | 2,858 | 4,560 | 7,469 | 32.4% | | 3.3% | | | | | | |
| Wrath, Rank 12 (Nature) | 149,849 | 6.9% | 14/14 | 4,243 | 10,704 | 16,842 | 57.1% | | 4.2% | | | | | | |
| Vampiric Touch, Rank 5 (Shadow) | 141,478 | 6.5% | | | | | | | | | 25 | 3,287 | 5,659 | 7,651 | 2.0% |
| Unstable Affliction, Rank 5 (Shadow) | 106,934 | 4.9% | | | | | | | | | 25 | 2,166 | 4,277 | 6,813 | 3.2% |
| Melee: Physical (Physical) | 82,809 | 3.8% | 33/34 | 84 | 2,509 | 8,999 | 12.1% | 2.9% | | 18.2% | | | | | |
| Curse of Agony, Rank 9 (Shadow) | 69,812 | 3.2% | | | | | | | | | 48 | 705 | 1,454 | 2,103 | 4.6% |
| Death and Decay (Shadow) | 55,958 | 2.6% | 78/81 | 507 | 717 | 1,649 | 2.6% | 3.7% | 5.5% | | | | | | |
| Auto Shot (Physical) | 49,727 | 2.3% | 11/11 | 2,717 | 4,521 | 7,433 | 45.5% | | | | | | | | |
| Shadow Word: Pain, Rank 12 (Shadow) | 46,062 | 2.1% | | | | | | | | | 18 | 1,651 | 2,559 | 4,566 | 6.6% |
| Devouring Plague, Rank 9 (Shadow) | 41,484 | 1.9% | | | | | | | | | 14 | 1,886 | 2,963 | 4,654 | 1.4% |
| Frost Fever (Frost) | 32,451 | 1.5% | | | | | | | | | 40 | 497 | 811 | 1,282 | 5.2% |
| Death Strike, Rank 5 (Physical) | 31,962 | 1.5% | 3/3 | 4,826 | 10,654 | 13,710 | 66.7% | | | | | | | | |
| Haunt, Rank 4 (Shadow) | 31,901 | 1.5% | 6/6 | 3,342 | 5,317 | 10,185 | 33.3% | | 5.5% | | | | | | |
| Icy Touch, Rank 5 (Frost) | 28,116 | 1.3% | 11/11 | 1,149 | 2,556 | 4,224 | 54.5% | | 2.9% | | | | | | |
| Blood Plague (Shadow) | 26,297 | 1.2% | | | | | | | | | 29 | 579 | 907 | 1,295 | 6.7% |
| Languish (Nature) | 24,812 | 1.1% | | | | | | | | | 9 | 562 | 2,757 | 5,768 | |
| Plague Strike, Rank 6 (Physical) | 17,783 | 0.8% | 6/6 | 1,208 | 2,964 | 7,689 | 16.7% | | | | | | | | |
| Death Coil (Shadow) | 17,567 | 0.8% | 3/3 | 4,040 | 5,856 | 8,978 | 33.3% | | 2.2% | | | | | | |
| Moonfire, Rank 14 (Arcane) | 16,309 | 0.8% | 1/1 | 885 | 885 | 885 | 100.0% | | | | 8 | 1,494 | 1,928 | 2,111 | 6.8% |
| Serpent Sting, Rank 12 (Nature) | 15,556 | 0.7% | | | | | | | | | 14 | 828 | 1,111 | 1,219 | 5.1% |
| Steady Shot, Rank 4 (Physical) | 15,087 | 0.7% | 3/3 | 2,672 | 5,029 | 6,599 | 66.7% | | | | | | | | |
| Aimed Shot, Rank 9 (Physical) | 14,939 | 0.7% | 2/2 | 3,892 | 7,470 | 11,047 | 50.0% | | | | | | | | |
| Frost Strike, Rank 6 (Frost) | 14,482 | 0.7% | 3/4 | 1,795 | 4,827 | 7,576 | 66.7% | 25.0% | 4.5% | | | | | | |
| Wild Quiver Auto Shot (Nature) | 13,657 | 0.6% | 2/2 | 5,948 | 6,828 | 7,709 | 100.0% | | 4.5% | | | | | | |
| Chimera Shot, Rank 1 (Nature) | 13,489 | 0.6% | 1/1 | 13,489 | 13,489 | 13,489 | 100.0% | | 3.8% | | | | | | |
| Piercing Shots (Physical) | 12,002 | 0.6% | | | | | | | | | 23 | 362 | 522 | 622 | |
| Necrosis (Shadow) | 9,872 | 0.5% | 10/10 | 554 | 987 | 1,800 | | | 7.1% | | | | | | |
| Improved Devouring Plague (Shadow) | 9,796 | 0.5% | 2/2 | 4,452 | 4,898 | 5,344 | | | | | | | | | |
| Heart Strike, Rank 6 (Physical) | 9,233 | 0.4% | 2/2 | 4,580 | 4,616 | 4,653 | | | | | | | | | |
| Chimera Shot - Serpent (Nature) | 7,313 | 0.3% | 1/1 | 7,313 | 7,313 | 7,313 | 100.0% | | 4.0% | | | | | | |
| Drain Life (Shadow) | 7,253 | 0.3% | 2/2 | 2,906 | 3,626 | 4,347 | | | | | | | | | |
| Silencing Shot (Physical) | 6,714 | 0.3% | 2/2 | 3,142 | 3,357 | 3,572 | 100.0% | | | | | | | | |
| Drain Soul, Rank 6 (Shadow) | 6,325 | 0.3% | | | | | | | | | 1 | 6,325 | 6,325 | 6,325 | |
| Mind Blast, Rank 13 (Shadow) | 5,862 | 0.3% | 1/1 | 5,862 | 5,862 | 5,862 | | | 8.9% | | | | | | |
| Blood Boil, Rank 4 (Shadow) | 3,891 | 0.2% | 4/4 | 630 | 973 | 1,408 | | | 3.5% | | | | | | |
| Blood Strike, Rank 6 (Physical) | 1,594 | 0.1% | 1/1 | 1,594 | 1,594 | 1,594 | | | | | | | | | |
| Interrupt, Rank 1 (Physical) | 0 | 0.0% | 0/2 | | | | | 100.0% | | | | | | | |
